Name
Oon Chern Ein
Current Position
Associate Professor
chern.oon@usm.my
Office Telephone
+604-6534879
Qualifications
BSc in Biotechnology (First Class Hon), Universiti Kebangsaan Malaysia
DPhil in Medical Oncology, University of Oxford, UK
Postdoctoral fellow at Karolinska Institutet, Sweden
Affiliations
Member of the Global Young Academy (GYA)
Member of the American Association for cancer Research (AACR)
Ambassador of the European Association for Cancer Research (EACR)
Member of the Young Scientists Network-Academy of Sciences Malaysia
Lifetime member of the Association of Union for International Cancer Control (UICC) Fellows
Member of the British Association for Cancer Research (BACR)
Visiting researcher at the National University of Singapore, Singapore (August 2014- October 2014)
Visiting researcher at the Nanyang Technological University, Singapore (April 2015- June2015)
Visiting fellow at the Nanyang Technological University, Singapore (July 2016- August 2016)
Achievements
The Malaysian Invention and Design Society (MINDS) Young Women Scientist Award, Year 2020
The Excellent Service Medal (Ministry of Higher Education), Year 2019
The British Council Study UK Alumni Award (Professional Achievement Category), Year 2020
Anugerah Akademik Harapan Negara (The Promising Academician Award) -Ministry of Higher Education, Year 2019
The Women of the Future- South East Asia (Science, Technology and Digital Category), Year 201
The National Young Scientist Award -Ministry of Science and Technology, Year 2018
The National Cancer Council (MAKNA) Cancer Research Award, Year 2016
The Union for International Cancer Control Fellowship, Year 2016
L’Oreal-UNESCO for Women in Science - National Fellowship, Year 2015
Lindau Nobel Laureate Meeting, Germany- Participant, Year 2015
Exiqon Young Scientist Award- South East Asia, Year 2014
Dr Ranjeet Bhagwan Singh Medical Research Trust Fund, Year 2014
Selected Publications
1. Y.T. Lee, Y.J. Tan, M. Falasca, C.E. Oon. Cancer-Associated Fibroblasts: Epigenetic Regulation and Therapeutic Intervention in Breast Cancer. Cancers, 2020, 12 (10), 2949 (Cancers, Q1 Impact factor 6.126)
2. YJ Tan, YT Lee, SH Petersen, G Kaur, K Kono, SC Tan, AMSA Majid, CE Oon. BZD9L1 sirtuin inhibitor as a potential adjuvant for sensitization of colorectal cancer cells to 5-fluorouracil. Therapeutic Advances in Medical Oncology 2019; Vol 11 (Q1, Impact factor 6.852)
3. AV Subramaniam, AHS Yehya, CW Kang, X Wang, CE Oon. Epigenetics: The master control of endothelial cell fate in cancer. Life sciences 2019 Sep 01;232:116652 (Q2, Impact factor 3.647)
4.Tan YJ, Lee YT, Yeong KY,Petersen SH, Kono K, Tan SC, Oon CE. Anticancer activities of a benzimidazole compound through sirtuin inhibition in colorectal cancer. 2018 Aug 1. Future Med Chem, Vol 10, No. 17. (Q2, Impact factor 3.617)
5. Yehya, A., Muhammad, A.,Kaur, G., Ahmed, L., Shah, A.M., Oon, C.E. Toxicological studies of standardized ethanol extract of Orthosiphon stamineus (Misai Kucing) in combination with gemcitabine in athymic nude mice model. Journal of Advanced Research. 2019:15, 59-68 (Q1, Impact factor 6.992)
6. Lee YT, Tan YJ, Oon CE. Molecular targeted therapy: Treating cancer with specificity. Eur J Pharmacol. 2018;834:188-196. (Q2, Impact factor 3.17)
7. Cheng, W.K and Oon, C.E. How glycosylation aids tumour angiogenesis: an updated review. Biomedicine and Pharmacotherapy.2018: 103, 1246-1252 (Q2, Impact factor 3.457)
10. Yehya, A., Muhammad, A., Petersen, S., Subramaniam, A., Kono, K.,Shah, A.M., Oon, C.E. Angiogenesis: managing the culprits behind tumourigenesis and metastasis. 2018. Medicina, Vol 54: 8-28 (Q3, Impact factor 1.429)
11. Oon CE, Bridges E, Sheldon H, Sainson RCA, Jubb A, Turley H, Leek R, Buffa F, Harris AL, Li JL. Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth. Oncotarget. (2017) 20;8(25):40115-40131. doi: 10.18632/oncotarget.16969.
12. AHS Yehya, M Asif, YJ Tan, S Sasidharan, AMSA Majid, CE Oon. Broad spectrum targeting of tumor vasculature by medicinal plants: An updated review. Journal of Herbal Medicine . Volume 9, September 2017, Pages 1-13 (Q2, Impact factor: 1.327)
13. Yeong, K.Y. and Oon, C.E. Sirtuin inhibitors: An overview from medicinal chemistry perspective. Anti-Cancer Agents in Medicinal Chemistry (2016), vol. 16(8) E-pub ahead of print (Q2, Impact factor: 2.598 )
14. K.Y. Yeong , M.A. Ali, C.W. Ang, S.C. Tan , C.E. Oon, A. N. Shirazi, K. Parang.
Discovery of a potent and highly fluorescent sirtuin inhibitor. DOI: 10.1039/C5MD90057C, Med. Chem. Commun, 2015, 6, 1857-1863 (Q1, Impact factor: 2.495)
15. Oon, C.E., Strell, C., Yeong, K.Y., Ostman, A., Prakash, J. SIRT1 inhibition in pancreatic cancer models; contrasting effects in vitro and in vivo. European Journal of Pharmacology (2015), vol (15)757:59-67. (Q2, Impact factor: 2.896) 16
16. Oon, C.E. and Harris, A.L. New pathways and mechanisms regulating and responding to deltalike 4-Notch signalling in tumour angiogenesis. Biochem Soc Trans (2011), vol 39(6):1612-8. (Q1, Impact factor: 2.765)
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