Khairul Mohd Fadzli Mustaffa

Dr Khairul New infografik template 2022



Khairul Mohd Fadzli Mustaffa

Current Position



Office Telephone



PhD in Tropical Medicine, University of Liverpool, 2012

MSc in Pharmacology, Universiti Sains Malaysia, 2008

BSc in Biotechnology, Universiti Putra Malaysia, 2002


The International Society on Aptamers (INSOAP)

Malaysian Scientific Association (MSA)

Malaysian Malaria Network

Research Interests

Molecular therapeutics,


Research Overview 1

Molecular therapeutics

The current focus is understanding molecular and cellular interaction that contributed to severe malaria development, with an emphasis on discovery of novel compounds (natural and synthetic compounds) and potential new biomarkers for therapeutic interventions.

Research Overview 2


Theranostics merging therapeutic and diagnostics to advance personalized medicine especially Point-of-Care (POC) of patients. At the moment, the lab developing RNA and DNA aptamer against a diverse set of target

biomarkers as an alternative of monoclonal antibody for infectious diseases diagnostics and therapy.

Selected Publications

1. Aptamer Technology: Adjunct Therapy for Malaria. Nik Kamarudin NAA, Mohammed NA, Mustaffa KMF. Biomedicines. 2017 Jan 4;5(1).

2. From the Natural Compound (+)-Epigallocatechin Gallate to a Simplified Synthetic Analogue as a Cytoadherence Inhibitor for Plasmodium falciparum.Gemma, Sandra; Brogi Simone; Patil, Pradeep; Brindisi, Margherita; Butini, Stefania; Novellino,   Ettore; Brown, Alan; Higgins, Matthew; Mustafa, Khairul; Szestak, Tadge; Craig, Alister; Campiani, Giuseppe. The Royal Society of Chemistry. 2014 Dec 16;4(9):4769.

3. Cytoadherence and severe malaria. Craig AG, Khairul MF, Patil PR. Malays J Med Sci. 2012 Apr;19(2):5-18.

4. Automated  counting for Plasmodium falciparum cytoadherence experiments. 2.     Paton D, Faragher B, Mustaffa KM, Szestak T, Barret SD, Craig AG. Malar. J. 2011 Apr 16:10:91.

5. Roxithromycin reverses chloroquine and mefloquine resistance in Plasmodium falciparum in vitro. T. H. Min, M. F. M. Khairul, J. H. Low, C. H. Che Nasriyyah, A. Noor A’shikin, M. N. Norazmi, M. Ravichandran and S. S. Raju. Exp Parasitol. 2007 Apr;115(4):387-92.

6. Fluoxetine potentiates chloroquine and mefloquine effect on multidrug-resistant Plasmodium falciparum in vitro. Khairul MF, Min TH, Low JH, Nasriyyah CH, A'shikin AN, Norazmi MN, Ravichandran M, Raju SS. Jpn J Infect Dis. 2006 Oct;59(5):329-31.

Author Links

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