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INSTITUTE FOR RESEARCH IN MOLECULAR MEDICINE

Screening and Confirmatory Tests for Typhoid Carriers: Enhancing Detection and Prevention 

Screening and Confirmatory Tests for Typhoid and Typhoid Carriers: Enhancing Detection and Prevention

Typhoid fever, caused by Salmonella Typhi, remains a significant public health concern, with chronic carriers acting as potential reservoirs for transmission. Early detection and identification of typhoid carriers are critical to prevent outbreaks and implement appropriate interventions. As food handlers have the potential to act as sources of disease transmission, the monitoring efforts are essential in maintaining food safety and preventing outbreaks. 

Implementing both screening and confirmatory tests for typhoid carriers provides several key benefits. Early detection of carriers allows for timely medical intervention and the initiation of appropriate treatment regimens. This reduces the risk of disease transmission, preventing outbreaks in communities and healthcare settings. Additionally, identifying carriers facilitates targeted contact tracing, enabling the isolation and treatment of individuals at high risk of infection. Furthermore, understanding the carrier status of individuals helps in developing preventive measures, such as vaccination campaigns and educational programs, to curb typhoid transmission and improve public health outcomes. 

INFORMM's expertise in the Dot Blot assay has positioned it as a go-to center for typhoid testing in Kelantan, Malaysia. By leveraging this technique's high accuracy and efficiency, INFORMM plays a vital role in providing timely and reliable diagnostic results, enabling healthcare professionals to diagnose typhoid infections promptly, including identifying typhoid carriers. 

INFORMM collaborates closely with Pejabat Kesihatan Awam di seluruh Kelantan to enhance the monitoring and management of typhoid cases among food handlers. INFORMM's expertise in using the Dot Blot assay enables Pejabat Kesihatan Awam di seluruh Kelantan to accurately screen and identify typhoid carriers among this at-risk population. 

As a leading diagnostic method, the Dot Blot assay is widely employed by INFORMM for the rapid and sensitive detection of specific antigens or antibodies associated with various infectious agents, including Salmonella typhi. INFORMM's team of skilled researchers utilizes the Dot Blot assay to identify and quantify typhoid-related antigens or antibodies in patient samples. The assay's simplicity, cost-effectiveness, and ability to process numerous samples simultaneously make it an essential tool in combating infectious diseases. 

Recognizing the significance of early detection and intervention, INFORMM collaborates closely with Pejabat Kesihatan Awam di seluruh Kelantan to enhance the monitoring and management of typhoid cases among food handlers. INFORMM's expertise in using the Dot Blot assay enables Pejabat Kesihatan Awam di seluruh Kelantan to accurately screen and identify typhoid carriers among this at-risk population. 

By partnering with INFORMM, Pejabat Kesihatan Awam di seluruh Kelantan can access advanced diagnostic capabilities and stay at the forefront of typhoid surveillance efforts. The collaboration ensures that timely and precise results are obtained, leading to prompt treatment, appropriate isolation measures, and targeted educational campaigns for food handlers. The synergy between INFORMM's diagnostic prowess and public health oversight enhances Malaysia's ability to effectively manage typhoid infections and prevent potential. 

Contact Person: Assoc. Professor Dr Aziah Ismail (aziahismail@usm.my)

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Industry Community Advisory Panel (ICAP)

In line with USM’s aim to establish a closer network with the industry and community, INFORMM has appointed the following Industry and Community Advisory Panel (ICAP) members.

We thank our ICAP members for their time and contribution to enhance our industry and community outreach programmes.

More information concerning ICAP, under the USM's Industry and Community Network can be found here: USM ICAP.

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Undergraduate Research Program (UROP)

Undergraduate Research Opportunity Programme (UROP) at INFORMM is a training model founded in 2019, designed to promote and cultivate research interest and research-oriented critical thinking among medical/biomedical/health sciences undergraduate students. The training is one of INFORMM’s strategies in encouraging undergraduate students to embark in postgraduate studies and prepare them for an innovative journey in research. The programme is also among other INFORMM’s action-contributions in supporting the two SDGs - SDG 3 Good Health & Well-being and SDG 4 Quality Education, inspired to ensure superior quality of postgraduate (MSc & PhD) students to support the desire for research innovations in medical/biomedical/health at USM and for Malaysia. The essentials of UROP include lectures on molecular biology - its relation to the mechanism of disease, and demos & hands-on practical on techniques in molecular biology - its utilization in fundamental research as well as disease diagnostics. The duration for UROP is about three to four weeks and currently, free-of-charge to USM undergraduates. Currently, UROP is only conducted at INFORMM Health Campus, Kelantan.

Updated: 30 July 2023

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Academic/Industry Fellow

 

Industry Fellow 

  Mr Tang

Tang Kok Mun
Biogenes Technologies Sdn. Bhd. MALAYSIA
tang.rapid@gmail.com
 

 

Mr. Tang Kok Mun is the co-founder and CEO of Biogenes Technologies, a Malaysian-based company focusing on development and commercialisation of aptamer-based molecular diagnostic technologies for applications in human healthcare, animal healthcare, agricuture, aquaculture, food safety and pollution monitoring. Mr Tang have over 15+ years of experience in bringing technologies from R&D stage to commercial markets. Some of his earlier startups and projects are in technology areas such as smart water monitoring system, biomass utilization for renewable energy and bio-based chemicals, as well as genomics in aquaculture. Mr. Tang majors in Chemical Engineering and Master in Business Administration from University of Malaya, as well as having graduated from Stanford University Center of Professional Development in Entrepreneurship. He also holds the position as one of panel experts in Malaysian Rubber Council (MRC).

ACADEMIC FELLOW

 satvinder dhaliwal edited

Emeritus Professor Satvinder Singh Dhaliwal
Curtin University AUSTRALIA

satvinder.dhaliwal@usm.my

 

Professor Dhaliwal has worked as a Biostatistician for the past 30 years and has accumulated extensive experience, both nationally and internationally, on the practical application of Statistics/Biostatistics in a wide variety of situations. Prof Dhaliwal’s research interest includes the application of Biostatistics in the fields of Public Health Research and Clinical Research. He specializes in the development of Clinical Prediction Models in Medical Research. Prof Dhaliwal has published in excess of 200 journal articles (Google Scholar H-index is 50 with over 9,400 citations). His publications have had a significant impact and were often the result of successful national and international research collaborations. Prof Dhaliwal is an Emeritus Professor of Biostatistics and Health Research at Curtin University, Australia. Prof Dhaliwal also holds and Adjunct Professor position with Duke-NUS Medical School in Singapore and is a Professor (Research and Statistics) at Singapore University of Social Sciences. Prof Dhaliwal is also commissioned as a Consultant Statistician to various private and government organizations in Australia and Singapore.

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Undergraduate Research Opportunity @ INFORMM

Undergraduate Research Opportunity Programme (UROP) at INFORMM is a training model founded in 2019, designed to promote and cultivate research interest and research-oriented critical thinking among medical/biomedical/health sciences undergraduate students. The training is one of INFORMM’s strategies in encouraging undergraduate students to embark in postgraduate studies and prepare them for an innovative journey in research. The programme is also among other INFORMM’s action-contributions in supporting the two SDGs - SDG 3 Good Health & Well-being and SDG 4 Quality Education, inspired to ensure superior quality of postgraduate (MSc & PhD) students to support the desire for research innovations in medical/biomedical/health at USM and for Malaysia. The essentials of UROP include lectures on molecular biology - its relation to the mechanism of disease, and demos & hands-on practical on techniques in molecular biology - its utilization in fundamental research as well as disease diagnostics. The duration for UROP is about three to four weeks and currently, free-of-charge to USM undergraduates. Currently, UROP is only conducted at INFORMM Health Campus, Kelantan.

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